{"id":1094,"date":"2019-08-21T11:25:11","date_gmt":"2019-08-21T11:25:11","guid":{"rendered":"http:\/\/200.17.196.19\/dac\/?page_id=1094"},"modified":"2019-11-13T16:53:48","modified_gmt":"2019-11-13T16:53:48","slug":"linhas-de-pesquisa","status":"publish","type":"page","link":"https:\/\/saude.ufpr.br\/dac\/linhas-de-pesquisa\/","title":{"rendered":"Linhas de pesquisa"},"content":{"rendered":"\n\n\n\n\t\n\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t
Docente<\/th>\u00c1rea<\/th>IC\/PVA<\/th>\n<\/tr>\n<\/thead>\n
Fabiane G. de Moraes Rego<\/td>Avalia\u00e7\u00e3o de biomarcadores laboratoriais e moleculares em crian\u00e7as e adolescentes saud\u00e1veis e portadores de diabetes mellitus tipo 1<\/td>Sim<\/td>\n<\/tr>\n
<\/td><\/td><\/td>\n<\/tr>\n
Izabella C. R. Santos Weiss<\/td>Avalia\u00e7\u00e3o de biomarcadores laboratoriais e moleculares em processos inflamat\u00f3rios<\/td>Sim<\/td>\n<\/tr>\n
<\/td><\/td><\/td>\n<\/tr>\n
Glaucio Valdameri<\/td>Bioqu\u00edmica farmacol\u00f3gica e molecular do c\u00e2ncer<\/td>Sim<\/td>\n<\/tr>\n
<\/td><\/td><\/td>\n<\/tr>\n
Karina Bettega Felipe<\/td>Farmacologia, Bioqu\u00edmica, Biologia Celular e molecular do c\u00e2ncer<\/td>Sim<\/td>\n<\/tr>\n
<\/td><\/td><\/td>\n<\/tr>\n
Mauren Isfer Anghebem<\/td>An\u00e1lises Cl\u00ednicas<\/td>Sim<\/td>\n<\/tr>\n
<\/td><\/td><\/td>\n<\/tr>\n
Meri Bordignon Nogueira<\/td>Infec\u00e7\u00f5es Virais em Crian\u00e7as, Imunocomprometidos.<\/td>Sim<\/td>\n<\/tr>\n
<\/td><\/td><\/td>\n<\/tr>\n
Vivian Rotuno Moure Valdameri<\/td>Bioqu\u00edmica, biologia molecular e estrutural<\/td>Sim<\/td>\n<\/tr>\n
<\/td><\/td><\/td>\n<\/tr>\n
Marcel Henrique Marcondes Sari<\/td>S\u00edntese de evid\u00eancias cient\u00edficas em Ci\u00eancias Biom\u00e9dicas: Constru\u00e7\u00e3o de Revis\u00f5es de Escopo<\/td>Sim<\/td>\n<\/tr>\n
<\/td><\/td><\/td>\n<\/tr>\n
rego@ufpr.br<\/td>\u00b7 \u00a0\u00a0\u00a0\u00a0\u00a0 Identifica\u00e7\u00e3o do polimorfismo C735T no gene MMP-2 em pacientes com e sem diabetes mellitus tipo 1.<\/td><\/td>\n<\/tr>\n
<\/td><\/td><\/td>\n<\/tr>\n
<\/td>\u00b7 \u00a0\u00a0\u00a0\u00a0\u00a0 Identifica\u00e7\u00e3o do polimorfismo rs3918242 no gene da MMP-9 em pacientes com e sem diabetes mellitus tipo 1.<\/td><\/td>\n<\/tr>\n
<\/td><\/td><\/td>\n<\/tr>\n
<\/td>\u00b7 \u00a0\u00a0\u00a0\u00a0\u00a0 Genotipagem do polimorfismo rs5742909 no gene CTLA-4 em pacientes com e sem diabetes mellitus tipo 1.<\/td><\/td>\n<\/tr>\n
<\/td><\/td><\/td>\n<\/tr>\n
<\/td>\u00b7 \u00a0\u00a0\u00a0\u00a0\u00a0 Estudo molecular do locus 2 diabetes mellitus insulino dependente e associa\u00e7\u00e3o com biomarcadores de controle glic\u00eamico em crian\u00e7as e adultos portadores de diabetes mellitus tipo 1.<\/td><\/td>\n<\/tr>\n
<\/td><\/td><\/td>\n<\/tr>\n
<\/td>\u00b7 \u00a0\u00a0\u00a0\u00a0\u00a0 Polimorfismos nos genes Foxa2, HNF-1\u03b1, LRH-1 e apoM no diabetes mellitus tipo 1<\/td><\/td>\n<\/tr>\n
<\/td><\/td><\/td>\n<\/tr>\n
<\/td>Avalia\u00e7\u00e3o de biomarcadores moleculares in vitro e in vivo em resposta ao tratamento com agentes antidiabetog\u00eanicos<\/td><\/td>\n<\/tr>\n
<\/td><\/td><\/td>\n<\/tr>\n
<\/td>\u00b7 \u00a0\u00a0\u00a0\u00a0\u00a0 Avalia\u00e7\u00e3o de biomarcadores laboratoriais e moleculares em indiv\u00edduos saud\u00e1veis e portadores de diabetes mellitus tipo 2 e Avalia\u00e7\u00e3o Epigen\u00e9tica in vitro de genes da linhagem celular HepG2.<\/td><\/td>\n<\/tr>\n
<\/td><\/td><\/td>\n<\/tr>\n
<\/td>\u00b7 \u00a0\u00a0\u00a0\u00a0\u00a0 Efeito do yacon (Smallanthus sonchifolius) e picolinato de cromo sobre par\u00e2metros metab\u00f3licos em ratos Wistar machos com resist\u00eancia \u00e0 insulina.<\/td><\/td>\n<\/tr>\n
<\/td><\/td><\/td>\n<\/tr>\n
<\/td>\u00b7 \u00a0\u00a0\u00a0\u00a0\u00a0 Polimorfismos nos genes envolvidos em processo inflamat\u00f3rio no diabetes mellitus tipos 1.<\/td><\/td>\n<\/tr>\n
<\/td><\/td><\/td>\n<\/tr>\n
<\/td>Avalia\u00e7\u00e3o de biomarcadores laboratoriais e moleculares em gestantes saud\u00e1veis e portadoras de diabetes mellitus<\/td><\/td>\n<\/tr>\n
<\/td><\/td><\/td>\n<\/tr>\n
<\/td>\u00b7 \u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Avalia\u00e7\u00e3o da albumina glicada, 1,5-anidroglucitol e outros biomarcadores laboratoriais e moleculares no diabetes mellitus .<\/td><\/td>\n<\/tr>\n
<\/td><\/td><\/td>\n<\/tr>\n
<\/td>Estudo da variabilidade gen\u00e9tica em genes associados com diabetes mellitus<\/td><\/td>\n<\/tr>\n
<\/td><\/td><\/td>\n<\/tr>\n
<\/td>\u00b7 \u00a0\u00a0\u00a0\u00a0\u00a0 Polimorfismos nos genes SUMO4 e MMP2 no diabetes mellitus .<\/td><\/td>\n<\/tr>\n
<\/td><\/td><\/td>\n<\/tr>\n
<\/td>\u00b7 \u00a0\u00a0\u00a0\u00a0\u00a0 Polimorfismos no gene VEGFA e seus receptores no diabetes mellitus tipos 2<\/td><\/td>\n<\/tr>\n
<\/td><\/td><\/td>\n<\/tr>\n
<\/td>\u00b7 \u00a0\u00a0\u00a0\u00a0\u00a0 Polimorfismos no gene TNF-\u03b1 e seus receptores no diabetes mellitus tipos 2<\/td><\/td>\n<\/tr>\n
<\/td><\/td><\/td>\n<\/tr>\n
izabellac@ufpr.br<\/td>\u00b7 \u00a0\u00a0\u00a0\u00a0\u00a0 Biomarcadores inflamat\u00f3rios associados \u00e0 retocolite ulcerativa em pacientes acompanhados no ambulat\u00f3rio de intestino do Servi\u00e7o de Gastroenterologia do Hospital de Cl\u00ednicas da Universidade Federal do Paran\u00e1<\/td><\/td>\n<\/tr>\n
<\/td><\/td><\/td>\n<\/tr>\n
<\/td>Bioqu\u00edmica, Biologia Molecular <\/td><\/td>\n<\/tr>\n
<\/td><\/td><\/td>\n<\/tr>\n
<\/td>\u00b7 \u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Gen\u00f4mica comparativa dos principais agentes causadores do Micetoma: uma importante doen\u00e7a tropical negligenciada.<\/td><\/td>\n<\/tr>\n
<\/td><\/td><\/td>\n<\/tr>\n
<\/td>\u00b7 \u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Identifica\u00e7\u00e3o molecular de esp\u00e9cies de fungos isolados de colmeias de abelhas sem ferr\u00e3o.<\/td><\/td>\n<\/tr>\n
<\/td><\/td><\/td>\n<\/tr>\n
gvaldameri@ufpr.br<\/td>\u00b7 \u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Transportadores ABC como novos alvos para o tratamento do c\u00e2ncer<\/td><\/td>\n<\/tr>\n
<\/td><\/td><\/td>\n<\/tr>\n
<\/td>\u00b7 \u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Identifica\u00e7\u00e3o e caracteriza\u00e7\u00e3o de novos inibidores n\u00e3o citot\u00f3xicos e espec\u00edficos para o transportador ABCG2<\/td><\/td>\n<\/tr>\n
<\/td><\/td><\/td>\n<\/tr>\n
karinabettega@ufpr.br<\/td>\u00b7 \u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Desenvolvimento de um software espec\u00edfico para avalia\u00e7\u00e3o do ensaio clonog\u00eanico e sugest\u00e3o de uma nova interpreta\u00e7\u00e3o dos resultados obtidos<\/td><\/td>\n<\/tr>\n
<\/td><\/td><\/td>\n<\/tr>\n
<\/td>\u00b7 \u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Estudo do efeito antitumoral de extrato de alcal\u00f3ides totais obtido de fitoter\u00e1pico elaborado a partir da casca de Aspidosperma subincanum<\/td><\/td>\n<\/tr>\n
<\/td><\/td><\/td>\n<\/tr>\n
<\/td>\u00b7 \u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 A via do \u00e1cido araquid\u00f4nico como poss\u00edvel alvo para o efeito antitumoral de Lafoensia pacari em carcinoma colorretal<\/td><\/td>\n<\/tr>\n
<\/td><\/td><\/td>\n<\/tr>\n
<\/td>\u00b7 \u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Avalia\u00e7\u00e3o do potencial citot\u00f3xico, antiproliferativo e antimetast\u00e1tico in vitro de extrato de pr\u00f3polis de abelha Tetragona clavipes associado a agentes antineopl\u00e1sicos<\/td><\/td>\n<\/tr>\n
<\/td><\/td><\/td>\n<\/tr>\n
<\/td>\u00b7 \u00a0\u00a0\u00a0\u00a0\u00a0\u00a0 Avalia\u00e7\u00e3o do potencial citot\u00f3xico, antiproliferativo e antimetast\u00e1tico in vitro de pr\u00f3polis proveniente do munic\u00edpio de Piraquara-PR<\/td><\/td>\n<\/tr>\n
<\/td><\/td><\/td>\n<\/tr>\n
mauren.isfer@ufpr.br<\/td>\u00b7 \u00a0\u00a0\u00a0 Biomarcadores inflamat\u00f3rios e polimorfismos gen\u00e9ticos associados \u00e0s complica\u00e7\u00f5es vasculares do diabetes mellitus.<\/td><\/td>\n<\/tr>\n
<\/td><\/td><\/td>\n<\/tr>\n
meribor@ufpr.br<\/td>Infec\u00e7\u00f5es virais em Ginecologia e Obstetr\u00edcia.<\/td><\/td>\n<\/tr>\n
<\/td><\/td><\/td>\n<\/tr>\n
<\/td>Sa\u00fade da Mulher<\/td><\/td>\n<\/tr>\n
<\/td><\/td><\/td>\n<\/tr>\n
<\/td>\u00b7 \u00a0\u00a0\u00a0\u00a0\u00a0 Impacto das Infec\u00e7\u00f5es respirat\u00f3rias virais em gestantes com notifica\u00e7\u00e3o de S\u00edndrome Respirat\u00f3ria Aguda Grave (SRAG), no per\u00edodo de 2015 a 2018<\/td><\/td>\n<\/tr>\n
<\/td><\/td><\/td>\n<\/tr>\n
<\/td>\u00b7 \u00a0\u00a0\u00a0\u00a0\u00a0 Caracteriza\u00e7\u00e3o Epidemiol\u00f3gica e Molecular do Parechov\u00edrus Humano no HC- UFPR<\/td><\/td>\n<\/tr>\n
vivian.moure@ufpr.br<\/td>\u00b7 \u00a0\u00a0\u00a0\u00a0\u00a0 Caracteriza\u00e7\u00e3o estrutural e funcional de prote\u00ednas envolvidas em processos patol\u00f3gicos<\/td><\/td>\n<\/tr>\n
Marcel Henrique Marcondes Sari
\nmarcelsari@ufpr.br<\/td>		Professor Colaborador do Programa de P\u00f3s-gradua\u00e7\u00e3o em Ci\u00eancias Farmac\u00eauticas - UFPR. \u00c1rea de concentra\u00e7\u00e3o: An\u00e1lises Cl\u00ednicas. Linha de Pesquisa: Marcadores moleculares em processos fisiol\u00f3gicos e patol\u00f3gicos\/Novas estrat\u00e9gias para tratamento de doen\u00e7as agudas e cr\u00f4nicas. Projeto de Pesquisa:\u00a0 \"Investiga\u00e7\u00e3o multifatorial de marcadores bioqu\u00edmicos em pacientes com dor cr\u00f4nica: da modelagem matem\u00e1tica \u00e0 avalia\u00e7\u00e3o pr\u00e9-cl\u00ednica em modelos animais de dor\"<\/td>Sim<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1615,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"class_list":["post-1094","page","type-page","status-publish","hentry"],"acf":[],"featured_image_src":null,"uagb_featured_image_src":{"full":false,"thumbnail":false,"medium":false,"medium_large":false,"large":false,"1536x1536":false,"2048x2048":false,"noticias-thumb":false,"banners-thumb":false,"maisnoticias-thumb":false,"post-thumbnail":false},"uagb_author_info":{"display_name":"Guilherme","author_link":"https:\/\/saude.ufpr.br\/dac\/author\/guilhermematos\/"},"uagb_comment_info":0,"uagb_excerpt":null,"publishpress_future_action":{"enabled":false,"date":"2026-05-03 07:13:08","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/saude.ufpr.br\/dac\/wp-json\/wp\/v2\/pages\/1094","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/saude.ufpr.br\/dac\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/saude.ufpr.br\/dac\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/saude.ufpr.br\/dac\/wp-json\/wp\/v2\/users\/1615"}],"replies":[{"embeddable":true,"href":"https:\/\/saude.ufpr.br\/dac\/wp-json\/wp\/v2\/comments?post=1094"}],"version-history":[{"count":2,"href":"https:\/\/saude.ufpr.br\/dac\/wp-json\/wp\/v2\/pages\/1094\/revisions"}],"predecessor-version":[{"id":2358,"href":"https:\/\/saude.ufpr.br\/dac\/wp-json\/wp\/v2\/pages\/1094\/revisions\/2358"}],"wp:attachment":[{"href":"https:\/\/saude.ufpr.br\/dac\/wp-json\/wp\/v2\/media?parent=1094"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}